Alcoholic prepartion for topical use



' tical Patented May-4, 1926.

UNITED STA rss rarsiir OF Flea.

onnrnron anus, or uon'rcmm, new mnsnx, Assreno'n, BY menu hssremms,

'I'O SETHB. HUNT, TRUSTEE,

or uorm'r nee -new YORK ALCOHOLIC. PREPARTION IE'OB TOPICAL USEiiomawing. v

To all whom it May concern:

Be itknown that I, GARLE'roN EnL1s, a citizen of the United States, anda resident of Montclair, in the county of Essex and State of New".Jersey, have invented certain new and useful Improvements in AlcoholicPreparation for Topical Use, of which the following is aspecification;

This invention relates to a method of treating propyll alcohol and tocertain roducts obtained therefrom, more speci callyproducts intendedfor application to the skin or clothing of persons and .consistin ofalcoholic preparations comprising propy alcohol and more specificallyisopropyl alcohol of a purified character preferably in conjunction withan essential oil or medici-z nal agent.'

The present' invention is concerned with alcohol particularly isopropylalcohol d]?- e g petroleum oils an the any hydrocarbon to yieldpropylene. The latter ma be associated with ot er olefines such asutylene, amylene and the like. The ases containing propylene may; bepasse into cold sulphuric acid of a strength say 1.8 specific gravityand absorption allowed to take place with the aproduction of what may betermed'an aci extract containing propyl sulphuric acid. This ma behydrolyzed to produce an alcoholic mix ure from'whichcrude ropyl alcoholis obtained by distillation. his is. accompanied .by

hydrocarbons or-other substances which impart a strong odor of adisagreeable character from the standpoint of alcoholic preparationsintended for medical or pharmaceupurposes. In order to prepare the propyalcohol in a form suitable for such applications I alcohol" the f lowingmanner. 5 to 10% of caustic soda is added and the alcohol heated toboiling or inany event warmed somewhat. -When heated to boiling a re-'flux condenser may be employed, the alcohol is then satur ted withcommonsalt and allowed to stan. Globules of oily material will se' aratefrom the impure product and when t e amount of this oil is considerableit maybe drawn ofi. However, there are still traces of oil in thealcohol and these may be removed by filtration through sawdust,charcoal, kieselguhr the like, espepreferably treat the crude 0Application filed Kay 28, 1919. Serial Nb. 298,843.

cially material of this character which has been treated with oil. Forexample bone black is allowed to take up sa'ylO to 20% or 1tsweight of apure oil such, for example, as refined mineral oil used for mediclnalpurposes, white Russian oil and the like, and fatty oils and waxes maybe .emplo ed in some cases. .Qn agitation of the di ute alcohol'withthis oil material or preferably 'by' filtration through the oilmaterial" the residual oil; matter in the alcohol is absorbed in the oilfiltration agent. A further purification may be effected by the additionof a few per cent of hydrogen peroxide and shaking with a small. amountof platinum or palladium catalyzer supported on asbestos or kieselguhr.The alcohol then ma be concentrated and rectified byv re:disti 'lat1onwhichmay be repeated if desired. The alcohol, 'when purified in themanner described or in an equivalent way, is in 'substantially' pureform and-practicallyiree from odors" of forei materials.

This alcohol may e employed in the man- Q ufacture of witchhazel extractand other extracts intended for external a plication,

bi for example distilling witch azel with t e alcohol in the presence ofsteam. Or

the purified isopropyl alcohol may be added toordinary witch hazelextract containing ethyl alcohol, such additions being in amountof 5 .to20% or more as may be desiredr g It has commonly been su posed thatpropyl alcohol was more toxic t an ethyl alcohbl and this may e true tosome extent in the case of primary propyl alcohol, buirobservw tionsmade with the secondary or isopropyl alcohol indicate that it is notirritating or harmful to the skin., Hence the purified bing" a cohol inplace of or inary grain alcohol. s 'As stated it is important thatalcohol used for such purposes should be free from empyreumatic 011s andthe like isoprop 1 alcohol may be emplo. ed as a ruba as these, even msmalliquantities, may have an irritating action Onthe skm.

Theisopropyl alcohol may also be em ployed advanta eously in perfumesand may be mixedand lended with various essential oils and perfuminprinciples.

ing the cruder oils such as oi of lavender, various oilsand the like andwill also i poratereadily with perfuming The sopropyl alcohol will.issolve and incordissolve, the more costly perfuming agents such as thevarious flower oils. Further more the refinedpropyl alcohol, especiallyif not containing more than about 5% of water and if free fromempyreumatic oils appears to have no deleterious effect on es sentialoils of this character. The amount of isopropyl alcohol which may beused in such perfumes may vary within considerable limits from say 5 or10% up to 90 or 95%. It may be used in admixture with ethyl alcohol ifdesired, in the place of isopropyl alcohol. As noted above, the presenceof'large amounts of water is undesirable whep using the alcohol withcertain perfuming principles and it is especially desirable not to havea large amount 01 isopropyl hydrate present. The hydrate of isopropylalcohol exists in several forms, all, of which are undesirable, in anylarge proportion, for certain purposes. Hence the alcohol should befreed from such hydrates to as great an extent as possible when the1,5sae1a synthetic perfuming agents and it also may be employed in thepreparation of hair tonics.

tion comprising purified isopropyl alcohol derived from propylene, andfree from empyreumatic oils.

2. In products intended for application to the skin or clothing, analcoholic preparation comprising a perfume oil incorporated withpurified isopropyl alcohol derived from propylene.

3. A perfume applicable to the skin or to clothing containing a perfumeoil dissolved ,in i'sopropyl alcohol.

4. In products intended for application to the skin or to clothing, analcoholic prepara-tion comprising a perfume oil incorporated with apurified and deodorized isopropyl alcohol containing no more than fivepercent of water and free from empyreupresence of these hydratesisobjectionable. matic oil and also substantially free from Theisopropyl alcohol prepared herein may be employed as a carrier forvarious alcoholic hydrates.

- CARLETON ELLIS.

